Progress in Human Embryology

A new life comes from a beautiful encounter between the sperm and the egg in the oviduct. The fertilized ovum proliferates and differentiates during the following 40 weeks. There are so many interesting and unpredictable events than a mother’s viewing of her embryo during the ultrasound examination. Who controlled the occurrence of these events? Embryo induction? Gene transcription? Epigenetic regulation? Or cell signaling? More clinical malformation cases and more scientific enlightenment.

开设学校：山东大学；学科：医药卫生、

Progress in Human Embryology课程：前往报名学习

Progress in Human Embryology视频慕课课程简介：

A new life comes from a beautiful encounter between the sperm and the egg in the oviduct. The fertilized ovum proliferates and differentiates during the following 40 weeks. There are so many interesting and unpredictable events than a mother’s viewing of her embryo during the ultrasound examination. Who controlled the occurrence of these events? Embryo induction? Gene transcription? Epigenetic regulation? Or cell signaling? More clinical malformation cases and more scientific enlightenment.

前往报名学习

Progress in Human Embryology课程列表：

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Week 1 Introduction of Human Embryology

-1.1 What is human embryology？

--1.1

--PPT

-1.2 Brief history of embryology

--1.2

--PPT

-1.3 Advances of modern embryology

--1.3

--PPT

-1.4 What is teratology?

--1.4

--PPT

-1.5 Research methods of human embryology

--1.5 Research methods of human embryology

--PPT

Week 2 Gametogenesis and fertilization

-2.1 Spermatogenesis

--2.1 Spermatogenesis

--PPT

--2.1

-2.2 Oogenesis

--2.2

--PPT

--2.2

-2.3 Fertilization

--2.3 Fertilization

--PPT

--2.3

-2.4 Genomic imprinting

--2.4 Genomic imprinting

--PPT

--Paper 1 Genomic imprinting parental influence on the genome.

--Paper 2 The discovery and importance of genomic imprinting

-2.5 Baby with three-parents

--2.5

--PPT

--Paper 1 Regulators weigh benefits of 'three-parent' fertilization

--Paper 2 Correction of the consequences of mitochondrial 3243A G mutation in the MT-TL1 gene causing

-Test for week 2

Week 3 First week and second week of development: Cleavage to implantation

-3.1 Cleavage

--3.1 Cleavage

--PPT

-3.2 implantation

--3.2 Implantation

--PPT

--3.2 Implantation

--3.2 Implantation

-3.3 What determines whether a blastomere forms inner cell mass or trophoblast

--3.3 What determines whether a blastomere forms inner cell mass and trophoblast?

--PPT

--Paper

-Test for week 3

Week 4 Third to eight week of development: Gastrulation and differentiation of trilaminar disc

-Gastrulation

--Gastrulation

--Gastrulation PPT

-Derivatives of ectoderm

--Derivatives of ectoderm

--Derivatives of ectoderm

-Derivatives of mesoderm

--Derivatives of mesoderm

--Derivatives of mesoderm

-Derivatives of endoderm

--Derivatives of endoderm

--Derivatives of endoderm

-Induction of the primitive streak

--Induction of the primitive streak

--Paper

-Teratogenesis associated with gastrulation

--Teratogenesis associated with gastrulation

--Paper

-Neural induction

--Neural induction

--Paper

-Test for week 4

Week 5 Fetal membrane and placenta

-Fetal membrane-Amnion

--Fetal membrane-Amnion

--Fetal membrane-Amnion PPT

-Fetal membrane-Yolk sac and allantois

--Fetal membrane-Yolk sac and allantois

--Fetal membrane-Yolk sac and allantois PPT

-Fetal membrane-Chorion

--Fetal membrane-Chorion

--Fetal membrane-Chorion PPT

-Fetal membrane-Umbilical cord

--Fetal membrane-Umbilical cord

--Fetal membrane-Umbilical cord PPT

-Placenta

--Placenta

--Placenta PPT

-HIV can be transmitted across placenta during parturition

--HIV can be transmitted across placenta during parturition

--paper

-Test for week 5

Week 6 Development of the head and neck

-Development of branchial arch and pharyngeal pouch

--Development of branchial arch and pharyngeal pouch

--Development of branchial arch and pharyngeal pouch PPT

-Development of face and clinical correlations

--Development of face and clinical correlations

--Development of face and clinical correlations PPT

-Development of palate and clinical correlations

--Development of palate and clinical correlations

--Development of palate and clinical correlations PPT

-SHH and craniofacial development

--SHH and craniofacial development

--Paper

-Test for week 6

Week 7 Development of the digestive and respiratory system

-Development of primitive gut

--Development of primitive gut

--Development of primitive gut PPT

-Development of foregut and clinical correlations

--Development of foregut and clinical correlations

--Development of foregut and clinical correlations PPT

-Development of digestive glands and clinical correlations

--Development of digestive glands and clinical correlations

--Development of digestive glands and clinical correlations PPT

-Development of the midgut and clinical correlations

--Development of the midgut and clinical correlations

--Development of the midgut and clinical correlations PPT

-Development of the hindgut and clinical correlations

--Development of the hindgut and clinical correlations

--Development of the hindgut and clinical correlations PPT

-Development of respiratory system and clinical correlations

--Development of respiratory system and clinical correlations

--Development of respiratory system and clinical correlations PPT

-Mesenchymal stem cell

--Mesenchymal stem cell

--Paper

-Test for week 7

Week 8 Development of urogenital system

-Development of the primordium of the urogenital system

--Development of the primordium of the urogenital system

--Development of the primordium of the urogenital system PPT

-Development of kidney and ureter

--Development of kidney and ureter

--Development of kidney and ureter PPT

-Development of the bladder and clinical correlations

--Development of the bladder and clinical correlations

--Development of the bladder and clinical correlations PPT

-Development of the gonad and clinical correlations

--Development of the gonad and clinical correlations

--Development of the gonad and clinical correlations PPT

-Development of the genital duct and clinical correlations

--Development of the genital duct and clinical correlations

--Development of the genital duct and clinical correlations PPT

-Wnt4/Sox9 and sex determination

--Wnt4/Sox9 and sex determination

-Test for week 8

-Spermatogonial stem cells

--Spermatogonial stem cells

Week 9 Development of cardiovascular system

-Formation of the heart tube

--Formation of the heart tube

--Formation of the heart tube PPT

-Partitioning of the primitive atrium

--Partitioning of the primitive atrium

--Partitioning of the primitive atrium PPT

-Partitioning of the primitive ventricle

--Partitioning of the primitive ventricle

--Partitioning of the primitive ventricle PPT

-Partitioning of truncus arteriosus and bulbus cordis

--Partitioning of truncus arteriosus and bulbus cordis

--Partitioning of truncus arteriosus and bulbus cordis PPT

-Fetal circulation

--Fetal circulation

--Fetal circulation PPT

-Circulatory Changes after birth

--Circulatory Changes after birth

--Circulatory Changes after birth PPT

-Intrauterine therapy of congenital heart disease

--Intrauterine therapy of congenital heart disease

--Paper

-Test for week 9

Appendix：Apoptosis and embryonic development

-Introduction of apoptosis

--Introduction of apoptosis

-Apoptosis and caspase

--Apoptosis and caspase

-Apoptosis and embryonic development

--Function of apoptosis

-Regulation of apoptosis-Bcl-2

--Regulation of apoptosis-Bcl-2

-Regulation of apoptosis-IAPs P53 NF-kB

--Regulation of apoptosis-IAPs P53 NF-kB

-Signaling pathway of apoptosis-Extrinsic pathway

--Signaling pathway of apoptosis-Extrinsic pathway

-Signaling pathway of apoptosis-Intrinsic pathway

--Signaling pathway of apoptosis-Intrinsic pathway

-Detection methods of apoptosis

--Detection methods of apoptosis

Progress in Human Embryology开设学校：山东大学

Progress in Human Embryology授课教师：

郭雨霁-副教授-山东大学-

山东大学医学院组织胚胎学与解剖学系副教授，参与组织学与胚胎学国家级精品课程的建设，曾获医学院英语讲课比赛一等奖，山东省微课教学比赛一等奖，山东大学青年教学能手，山东大学课堂教学质量优秀教师，山东省高等教育教学成果一等奖（第四位）。参与编写多部人民卫生出版社、科学出版社《组织学与胚胎学》国家级规划教材、主译《备孕圣经》、参译《奈特氏人体胚胎学彩色图谱》、《怀孕圣经》等。目前承担本科生、研究生及留学生的《组织学与胚胎学》、《医学形态学概述》、《人体结构与功能》、《临床胚胎学》、《干细胞研究进展》、《细胞信号转导与疾病》（全英文）等课程的教学工作。2007年赴美国新泽西州州立大学W. M. Keck Center for Collaborative Neuroscience，师从神经生物学著名教授Melitta Schachner进行了为期一年的学术交流，深入开展了有关脊髓损伤后内源性神经干细胞激活的研究，系统分析了脊髓损伤后内源性神经再生密切相关基因Sox11在脊髓损伤修复中的作用，承担国家自然基金、山东省自然基金、山东省中青年科学家奖励基金及中国博士后基金特别资助等多项课题，曾获山东省教育厅高校奖自然科学类三等奖。

刘尚明--山东大学-

刘尚明，男，山东大学副教授，硕士生导师。高等医学研究院转化医学共享平台主任、组织胚胎学系副主任。承担《组织学与胚胎学》、《医学形态学概论》、《人体胚胎学》、《人体结构与功能》、《医学超微结构》等课程的教学。先后参编人民卫生出版社、高等教育出版社《组织学与胚胎学》国家级规划教材的编写。参与组织学与胚胎学国家级精品课程及“人体解剖与组织胚胎系列课程国家级教学团队”的建设。主持“人体胚胎学特色课堂”获山东大学“双一流人才建设专项经费”支持、获校级教学成果一等奖一项。科研方面主要从事神经发育及胚胎畸形相关方面的研究，先后承担省自然科学基金、国家自然科学基金、中国博士后基金特别资助等项目。

王富武--山东大学-

张艳敏--山东大学-

张晓丽--山东大学-

郝晶--山东大学-

郝爱军--山东大学-

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