8.1 Abormalities in genes and proteins are the molecular basis of diseases资料文件与下载

Molecular Biology课程列表：

Week 1 （1.） Introduction

-1.1 The research content of molecular biology

--1.1 The research content of molecular biology

--1.1 The research content of molecular biology

-1.2 Important events in the development of molecular biology

--1.2 Important events in the development of molecular biology

--1.2 Important events in the development of molecular biology

-1.3 Molecular Biology and Related Disciplines

--1.3 Molecular Biology and Related Disciplines

--1.3 Molecular Biology and Related Disciplines

Week1 (2.) Genes and Genomes

-2.1 The Concept and Structure of Genes

--2.1 The Concept and Structure of Genes

--2.1 The concept and structure of genes

-2.2 Prokaryotic genome

--2.2 Prokaryotic genome

--2.2 Prokaryotic genome

-2.3 Eukaryotic genome

--2.3 Eukaryotic genome

--2.3 Eukaryotic genome

-2.4 Viral genome

--2.4 Viral genome

--2.4 Viral genome

-Unit assignment for week 1

-Discussion for week 1

Week2 Regulation of Gene Expression

-3.1 The common characteristics of gene expression in prokaryotes and eukaryotes

--3.1The common characteristics of gene expression in prokaryotes and eukaryotes

--3.1The common characteristics of gene expression in prokaryotes and eukaryotes

-3.2 Mechanism of gene expression regulation in prokaryotes

--3.2Mechanism of gene expression regulation in prokaryotes

--3.2Mechanism of gene expression regulation in prokaryotes

-3.3 Characteristics and regulation of genomic DNA expression in eukaryotes

--3.3 Characteristics and regulation of genomic DNA expression in eukaryotes

--3.3 Characteristics and regulation of genomic DNA expression in eukaryotes

-3.4 Regulation of eukaryotic gene expression at transcriptional and post-transcriptional level

--3.4Regulation of eukaryotic gene expression at transcriptional and post-transcriptional level

--3.4 Regulation of eukaryotic gene expression at transcriptional and post-transcriptional level

-Discussion for week 2

Week 3 Mechanisms of DNA Damage and Repair

-4.1 Causes and Consequences of DNA Damage

--4.1Causes and Consequences of DNA Damage

--4.1Causes and Consequences of DNA Damage

-4.2 Mismatch Repair and Direct Repair

--4.2 Mismatch Repair and Direct Repair

--4.2 Mismatch Repair and Direct Repair

-4.3 Base Excision Repair and Nucleotide Excision Repair

--4.3 Base Excision Repair and Nucleotide Excision Repair

--4.3 Base Excision Repair and Nucleotide Excision Repair

-4.4 Recombination Repair and SOS Repair System

--4.4 Recombination Repair and SOS Repair System

--4.4 Recombination Repair and SOS Repair System

-Unit assignment for week 3

-Discussion for week 3

Week 4 ( 1.) Basic Methods of Gene Structure and Expression Analysis

-5.1 DNA sequence analysis

--5.1 DNA sequence analysis

--5.1 DNA sequence analysis

-5.2 Polymerase chain reaction

--5.2 Polymerase chain reaction

--5.2 Polymerase chain reaction

-5.3 Real-time fluorescence quantitative PCR

--5.3 Real-time fluorescence quantitative PCR

--5.3 Real-time fluorescence quantitative PCR

-5.4 Nucleic acid molecular hybridization techniques

--5.4 Nucleic acid molecular hybridization techniques

--5.4 Nucleic acid molecular hybridization techniques

Week 4 ( 2.) Gene Cloning and Expression

-6.1 Principal enzymes used in gene cloning

--6.1 Principal enzymes used in gene cloning

--6.1 Principal enzymes used in gene cloning

-6.2 Vectors for Gene cloning

--6.2 Vectors for Gene cloning

-- 6.2 Vectors for Gene cloning

-6.3 The principal process of gene cloning

--6.3 The principal process of gene cloning

--6.3 The principal process of gene cloning

-6.4 The E.coli expression system

--6.4 The E.coli expression system

--6.4 The E.coli expression system

-Unit assignment for week 4

-Discussion for week 4

Week 5 Proteomics research methods

-7.1 The Concept and History of Proteomics

--7.1 The Concept and History of Proteomics

--7.1 The Concept and History of Proteomics

-7.2 Research method of proteome expression pattern--Two-dimensional electrophoresis

--7.2 Research method of proteome expression pattern--Two-dimensional electrophoresis

--7.2 Research method of proteome expression pattern--Two-dimensional electrophoresis

-7.3 Research method of proteome expression pattern-- Mass spectrometr

--7.3 Research method of proteome expression pattern-- Mass spectrometry

--7.3 Research method of proteome expression pattern-- Mass spectrometry

-7.4 Research Methods of Proteome Functional pattern

--7.4 Research Methods of Proteome Functional pattern

--7.4 Research Methods of Proteome Functional pattern

-Unit assignment for week 5

-Discussion for week 5

Week 6 (1. )Molecular basis of disease

-8.1 Abormalities in genes and proteins are the molecular basis of diseases

--8.1 Abormalities in genes and proteins are the molecular basis of diseases

--8.1 Abormalities in genes and proteins are the molecular basis of diseases

-8.2 Cell-related factors cause abnormal gene expression and cause disease

--8.2 Cell-related factors cause abnormal gene expression and cause disease

--8.2 Cell-related factors cause abnormal gene expression and cause disease

Week 6 (2.) Gene diagnosis

-9.1 Concept, Features and Strategies of Gene Diagnosis

--9.1 Concept, Features and Strategies of Gene Diagnosis

--9.1 Concept, Features and Strategies of Gene Diagnosis

-9.2 Molecular Biology Techniques Commonly Used in Gene Diagnosis

--9.2 Molecular Biology Techniques Commonly Used in Gene Diagnosis I

--9.2 Molecular Biology Techniques Commonly Used in Gene Diagnosis I

-9.3 Molecular Biology Techniques Commonly Used in Gene Diagnosis II

--9.3 Molecular Biology Techniques Commonly Used in Gene Diagnosis II

--9.3 Molecular Biology Techniques Commonly Used in Gene Diagnosis II

-9.4 Gene Diagnosis of Sickle Cell Disease

--9.4 Gene Diagnosis of Sickle Cell Disease

--9.4 Gene Diagnosis of Sickle Cell Disease

-Unit assignment for week 6

-Discussion for week 6

Week 7 Gene Therapy

-10.1 Basic strategies for gene therapy

--10.1 Basic strategies for gene therapy

--10.1 Basic strategies for gene therapy

-10.2 Gene transfer

--10.2 Gene transfer

--10.2 Gene transfer

-10.3 Gene interference

--10.3 Gene interference

--10.3 Gene interference

-10.4 Controlled expression of therapeutic genes

--10.4 Controlled expression of therapeutic genes

--10.4 Controlled expression of therapeutic genes

-10.5 Application of gene therapy

--10.5 Application of gene therapy

--10.5 Application of gene therapy

-Unit assignment for week 7

-Discussion for week 7

Final Exam

-Final Exam

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