Basic Molecular Biology 课程列表：

Chapter 1 The material basis of genetic information

- C1-Lecture 1 The past and present journey of molecular biology

--Key points C1-L1 The past and present journey of molecular biology

--Video-C1-L1 The past and present journey of molecular biology

--Discussion C1-L1

--Lecture 1-Homework

-C1-Lecture 2 The nature of genetic material

--Key points C1-L2 The nature of genetic material

--Video-C1-L2 The nature of genetic material

--Discussion C1-L2

--C1-Lecture 2-Homework

-C1-Lecture 3 Amazing DNA double helix

--Key points C1-L3 Amazing DNA double helix

--Video C1-L3 Amazing DNA double helix

--Discussion C1-L3

--C1-Lecture 3-Homework

-C1-Lecture 4 Supercoiled DNA

--Key points C1-L4 Supercoiled DNA

--Video C1-L4 Supercoiled DNA

--Discussion C1-L4

--C1-Lecture 4-Homework

-C1-Lecture 5 Denaturation, renaturation and hybridization

--Key points C1-L5 Denaturation, renaturation and hybridization

--Video C1-L5 Denaturation, renaturation and hybridization

--Discussion C1-L5

--C1-Lecture 5-Homework

-C1-Lecture 6 Nucleic acids extraction and gel electrophoresis

--Key points C1-L6 Nucleic acid extraction and gel electrophoresis

--Video C1-L6 Nucleic acid extraction and gel electrophoresis

--Discussion C1-L6

--C1-Lecture 6-Homework

-Chapter 1 Test

-Learning resources

--Web resources

-- References

Chapter 2 From gene to chromosome

-C2-Lecture 1 Genome does not equal to chromosome

--Key points C2-L1 Genomes are not equal to chromosomes

--Video C2-L1 Genomes are not equal to chromosomes

--Discussion C2-L1 Genomes are not equal to chromosomes

--C2-Lecture 1-Homework

-C2-Lecture 2 Nucleosomes and their Assembly

--Key points C2-L2 Nucleosomes and their Assembly

--Video C2-L2 Nucleosomes and their Assembly

--Discussion C2-L2 Nucleosomes and their Assembly

--C2-Lecture 2-Homework

-C2-Lecture 3 Higher order chromatin structure

--Key points C2-L3 Higher order chromatin structure

--Video C2-L3 Higher order chromatin structure

--Discussion C2-L3 Higher order chromatin structure

--C2-Lecture 3-Homework

-C2-Lecture 4 Chromatin modification and remodeling

--Key points C2-L4 Chromatin modification and remodeling

--Video C2-L4 Chromatin modification and remodeling

--Discussion C2-L4 Chromatin modification and remodeling

--C2-Lecture 4-Homework

-Chapter 2 Tests

-Learning resources

--Web resources

--References

Chapter 3 Who is in pairs? DNA replication

-C3-Lecture 1 Semiconservative DNA replication

--Key points C3-L1 Semiconservative DNA replication

--Video C3-L1 Semiconservative DNA replication

--Discussion C3-L1 Semiconservative DNA replication

--C3-Lecture1 Homework

-C3-Lecture 2 The mechanism of DNA polymerase

--Key points C3-L2 The mechanism of DNA polymerase

--Video C3-L2 The mechanism of DNA polymerase

--Discussion C3-L2 The mechanism of DNA polymerase

--C3-Lecture 2-Homework

-C3-Lecture 3 Process of DNA replication

--Key points C3-L3 Process of DNA replication

--Video C3-L3 Process of DNA replication

--Discussion C3-L3 Process of DNA replication

--C3-Lecture 3-Homework

-C3-Lecture 4 Regulation of DNA replication initiation

--Key points C3-L4 Regulation of DNA replication initiation

--Video C3-L4 Regulation of DNA replication initiation

--Discussion C3-L4 Regulation of DNA replication initiation

--C3-Lecture 4-Homework

-C3-Lecture 5 The end replication problem and telomere

--Key points C3-L5 The end replication problem and telomere

--Video C3-L5 The end replication problem and telomere

--Discussion C3-L5 The end replication problem and telomere

--C3-Lecture 5-Homework

-C3-Lecture 6 Let’s “cook” DNA

--Video C3-L6 Let’s “cook” DNA

--Discussion C3-L6 Let’s “cook” DNA

--C3-Lecture 6-Homework

- Chapter 3 Tests

-Learning resources

--Web resources

--References

Chapter 4 DNA mutation and repair

-C4-Lecture 1 Replication errors and the mismatch repair system

--Key points 4-1 Replication errors and the mismatch repair system

--Video 4-1 Replication errors and the mismatch repair system

--Discussion 4-1 Replication errors and the mismatch repair system

--C4-Lecture 1-Homework

-C4-Lecture 2 DNA damage

--Key points 4-2 DNA damage

--Video 4-2 DNA damage

--Discussion 4-2 DNA damage

--C4-Lecture 2-Homework

-C4-Lecture 3 DNA Repair

--Key points 4-3 DNA Repair

--Video 4-3 DNA Repair

--Discussion 4-3 DNA Repair

--C4-Lecture 3-Homework

-C4-Lecture 4 DNA Homologous Recombination

--Key points 4-4 DNA Homologous Recombination

--Video 4-4 DNA Homologous Recombination

--Discussion 4-4 DNA Homologous Recombination

--C4-Lecture 4-Homework

-C4-Lecture 5 Changing the natural gene sequences

--Key points 4-5 Changing the natural gene sequences

--Video 4-5 Changing the natural gene sequences

--Discussion 4-5 Changing the natural gene sequences

-Chapter 4 test

- Learning resources

--Web resources

--References

--References

Chapter 5 Transcription in prokaryotes

-C5-Lecture 1 RNA polymerase

--Key points 5-1 RNA polymerase

--Video 5-1 RNA polymerase

--Discussion 5-1 RNA polymerase

--C5-Lecture 1-Homework

-C5-Lecture 2 Transcription process in prokaryotes

--Key points 5-2 Transcription process in prokaryotes

--Video 5-2 Transcription process in prokaryotes

--Discussion 5-2 Transcription process in prokaryotes

--C5-Lecture 2-Homework

-C5-Lecture 3 Transcriptional regulation in bacterial I: Lac operon

--Key points 5-3 Transcriptional regulation in bacterial I: Lac operon

--Video 5-3 Transcriptional regulation in bacterial I: Lac operon

--Discussion 5-3 Transcriptional regulation in bacterial I: Lac operon

--C5-Lecture 3-Homework

-C5-Lecture 4 Transcriptional regulation in bacterial II: Tryptophan operon

--Key points 5-4 Transcriptional regulation in bacterial II: Tryptophan operon

--Video 5-4 Transcriptional regulation in bacterial II: Tryptophan operon

--Discussion 5-4 Transcriptional regulation in bacterial II: Tryptophan operon

--C5-Lecture 4-Homework

-Chapter 5 Test

-Learning resources

--References

Chapter 6 Transcription in eukaryotes

-Lecture 1 Eukaryotic RNA polymerase and promoter

--Key points 6-1 Eukaryotic RNA polymerase and promoter

--Video 6-1 Eukaryotic RNA polymerase and promoter

--Discussion 6-1 Eukaryotic RNA polymerase and promoter

--C6-Lecture 1-Homework

-Lecture 2 Transcription process in eukaryotic cell

--Key points 6-2 Transcription process in eukaryotic cell

--Video 6-2 Transcription process in eukaryotic cell

--Discussion 6-2 Transcription process in eukaryotic cell

--C6-Lecture 2-Homework

-Lecture 3 Transcription factors of eukaryotic cell

--Key points 6-3 Transcription factors of eukaryotic cell

--Video 6-3 Transcription factors of eukaryotic cell

--Discussion 6-3 Transcription factors of eukaryotic cell

--C6-Lecture 3-Homework

-Lecture 4 Epigenetic Regulation of gene expression

--Key points 6-4 Epigenetic Regulation of gene expression

--Video 6-4 Epigenetic Regulation of gene expression

--Discussion 6-4 Epigenetic Regulation of gene expression

--C6-Lecture 4-Homework

-Chapter 6 Test

-Learning resources

--Web resources

--References

Chapter 7 RNA Processing

-Lecture 1 RNA splicing

--Key points 7-1 RNA splicing

--Video 7-1 RNA splicing

--Discussion 7-1 RNA splicing

--C7-Lecutre 1-Homework

-Lecture 2 Cotranscriptional processing of nuclear pre-mRNA

--Key points 7-2 Cotranscriptional processing of nuclear pre-mRNA

--Video 7-2 Cotranscriptional processing of nuclear pre-mRNA

--Discussion 7-2 Cotranscriptional processing of nuclear pre-mRNA

--C7-Lecture 2-Homework

-Lecture 3 One gene one protein? Alternative RNA splicing

--Key points 7-3 One gene one protein? Alternative RNA splicing

--Video 7-3 One gene one protein? Alternative RNA splicing

--Discussion 7-3 One gene one protein? Alternative RNA splicing

--C7-Lecture 3-Homework

-Lecture 4 “Seeing” RNA

--Key points 7-4 “Seeing” RNA

--Video 7-4 “Seeing” RNA

--Discussion 7-4 “Seeing” RNA

-C7-Lecture 4-Homework

-Chapter 7 Test

-Learning Resources

--References

Chapter 8 Protein Synthesis, translation

-Lecture 1 Genetic codons and ribosome

--Key points 8-1 Genetic codons and ribosome

--Video 8-1 Genetic codons and ribosome

--Discussion 8-1 Genetic codons and ribosome

--C8-Lecture 1-Homework

-Lecture 2 Process of translation

--Key points 8-2 Process of translation

--Video 8-2 Process of translation

--Discussion 8-2 Process of translation

--C8-Lecture 2-Homework

-Lecture 3 Regulation of gene expression at Translational level

--Key points 8-3 Regulation of gene expression at Translational level

--Video 8-3 Regulation of gene expression at Translational level

--Discussion 8-3 Regulation of gene expression at Translational level

--C8-Lecture 3-Homework

-Lecture 4 Looking for your protein

--Key points 8-4 Looking for your protein

--Video 8-4 Looking for your protein

-Chapter 8 Test

-Learning resources

--References

--Life Cycle of an mRNA

--mRNA procesiing

--Protein synthesis

--SDS-PAGE

Final Exam

-Final Exam

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