当前课程知识点:Gateway to Medicine: An Introduction to the Field of Medicine > CH04 Get to know about tumor > 11 Heredity and tumor > Heredity and tumor
返回《Gateway to Medicine: An Introduction to the Field of Medicine》慕课在线视频课程列表
返回《Gateway to Medicine: An Introduction to the Field of Medicine》慕课在线视频列表
遗传与肿瘤
肿瘤会不会遗传
真正属于遗传的肿瘤
是少数属于遗传病的肿瘤
可以表现为是两个方面
一 呈常染色体显性遗传的肿瘤
这个治病因子传给子代
子代就会发病
或者带有这个致病基因
比如说 视网膜母细胞瘤
肾母细胞瘤
肾上腺
或者神经节的神经母细胞瘤
结肠多发性的腺瘤性的息肉病
神经纤维瘤病
这些肿瘤是属于遗传病
可以直接遗传
第二
表现的是常染色体隐性遗传的
遗传综合症
它的遗传的位点
比如说Bloom综合症
它累积的是DNA修复基因
Li-Fraumeni综合症
累积的是P53基因
从这个角度它是遗传的
但是
一旦这个DNA修复基因损伤
P53基因损伤
这些病人就容易患肿瘤
表现的是遗传易感性
也就是表现为家庭群聚现象
什么是遗传易感性肿瘤
这种肿瘤的遗传
它是多基因遗传
再加上环境因素
多方面的因素综合起来
来表现出家庭群聚现象
在肝癌 胃癌 乳腺癌
都有这种家庭群聚现象
那么爷爷患肝癌了
爸爸也患肝癌
那小孩子患肝癌的可能性怎么样
从这个家族来讲
他们的抗癌能力
受多基因遗传
但又同时处在同一个
生活环境当中
因此就可能容易患肝癌
表现做家庭的群聚现象
而不是肝癌的
真正的直接遗传
在西方我们有一种说法叫
外祖母的阴影
也就是说
外祖母患乳腺癌了
妈妈患乳腺癌了
判断到那个女孩
将来会不会患乳腺癌
那么
乳腺癌的发生也和遗传有关
它表现的也是
遗传易感性
而不是乳腺癌的一个直接的遗传
因此
绝大多数的肿瘤
都不是直接的遗传
-01-The basic condition of the air
--The basic condition of the air
-02-What is smog and its influence to the body
--What is smog and its influence to the body
-03-The structure and the function of human respiratory system
--The structure and the function of human respiratory system
-04-How the smog cause the human respiratory system disease
--How the smog cause the human respiratory system disease
-05-Asthma
--Asthma
-Exercise 01
-06-COPD
--COPD
-07-Lung cancer Ⅰ
-08-Lung cancer Ⅱ
-Exercise 02
-01 Dissection of genital organs
--Dissection of genital organs
-Exercise 01
-02 The formation of embryo and fetal appendage
--The formation of embryo and fetal appendage
-Exercise 02
-03 Characteristic of embryonic and fetal development
--Characteristic of embryonic and fetal development
-04 Maternal changes during pregnancy
--Maternal changes during pregnancy
-05 Four factors that affect childbirth
--Four factors that affect childbirth
-06 Mechanism of labor
-01 The energy requirement and the metabolic characteristics of kids
--The energy requirement and the metabolic characteristics of kids
-02 Need of the nutrition and metabolism of kids Ⅰ
--Need of the nutrition and metabolism of kids Ⅰ
-Exercise 01
-03 Need of the nutrition and metabolism of kids Ⅱ
--Need of the nutrition and metabolism of kids Ⅱ
-Exercise 02
-04 Guided feeding of infant Ⅰ
-Exercise 03
-05 Guided feeding of infant Ⅱ
-06 Guided feeding of infant Ⅲ
-01 Introduction
-02 What is tumor
-03 The general shape of tumor
-04 The atypia of the tumor
-05 Name and classification of the tumor
--Name and classification of the tumor
-Exercise 01
-06 The growing type of the tumor
--The growing type of the tumor
-07 Spread of tumor
-Exercise 02
-08 The grading and staging of tumors and the effects to the body
--The grading and staging of tumors and the effects to the body
-09 The difference between benign and malignant tumors
--The difference between benign and malignant tumors
-10 The environmental causes of cancer
--The environmental causes of cancer
-11 Heredity and tumor
-01 Overview
--Overview
-02 Sudden cardiac arrest
-Exercise 01
-03 Non-professional life support
--Non-professional life support
-Exercise 02
-04 Professional life support
-Exercise 03
-05 Adult advanced life support Ⅰ
--Adult advanced life support Ⅰ
-Exercise 04
-06 Adult advanced life support Ⅱ
--Adult advanced life support Ⅱ
-Exercise 05
-07 Electric defibrillation
-01 Introduction
-02 Risk factors and pathogenesis of atherosclerosis
--Risk factors and pathogenesis of atherosclerosis
-03 Pathological changes of atherosclerosis
--Pathological changes of atherosclerosis
-Exercise 01
-04 Atherosclerosis of vital organs
--Atherosclerosis of vital organs
-05 Coronary atherosclerotic heart disease
--Coronary atherosclerotic heart disease
-Tips 03
--Tips 03
-06 Primary hypertension
-Exercise 02
-07 The etiology and pathogenesis of hypertension
--The etiology and pathogenesis of hypertension
-08 The types and pathologic changes of essential hypertension
--The types and pathologic changes of essential hypertension
-Exercise 03
-01 Overview Ⅰ
-02 Overview Ⅱ
-03 What is virus
-Exercise 01
-04 The structure and functions of influenza viruses
--The structure and functions of influenza viruses
-Exercise 02
-05 Different type of influenza viruses
--Different type of influenza viruses
-Exercise 03
-06 Bird flu
--Bird flu
-Exercise 04
-07 Street virus
-Exercie 05
-01 Introduction
-02 Chronic gastritis caused by helicobacter pylori infection
--Chronic gastritis caused by helicobacter pylori infection
-Exercise 01
-03 Helicobacter pylori causes peptic ulcer
--Helicobacter pylori causes peptic ulcer
-Exercise 02
-04 Pathological changes of peptic ulcer
--Pathological changes of peptic ulcer
-Exercise 03
-05 Gastric cancer
-01 The evolution of biological motion
--The evolution of biological motion
-02 Biomechanics of human motion
--Biomechanics of human motion
-Exercise 01
-03 The perfect unity of function and structure
--The perfect unity of function and structure
-Exercise 02
-04 A brief history of trauma orthopedic development Ⅰ
--A brief history of trauma orthopedic development Ⅰ
-05 A brief history of trauma orthopedic development Ⅱ
--A brief history of trauma orthopedic development Ⅱ
-Exercise 03
-06 Sprain and fracture of the ankle joint
--Sprain and fracture of the ankle joint
-Exercise 04
-07 Ankle sprain
-Exercise 05
-08 Prevention of ankle sprain
-Final Exam