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Risk factors and pathogenesis of atherosclerosis课程教案、知识点、字幕

动脉粥样硬化的危险因素与发病

我们可以归结起以下几个方面

第一是致病的物质基础

主要表现的就是脂质代谢障碍

第二 是发病的条件

也就是血管壁的

抗脂的沉积的能力下降

第三

是其他影响因素

要么影响脂质代谢障碍

要么影响血管壁

抗脂的沉积能力下降

通常影响因素可以有高血压

吸烟 性别 年龄 饮食 内分泌

遗传和糖尿病等

我们具体把它展开

我们看发病的物质基础

脂质代谢障碍 高脂血症

表现血浆总胆固醇增高

或者甘油三酯增高

第二

易引起动脉粥样硬化的高危险性

血脂蛋白综合症

低密度脂蛋白

极低密度脂蛋白

甘油三酯和载脂蛋白B升高

而高密度脂蛋白

和载脂蛋白A降低

容易引起动脉粥样硬化

二 致病的条件

也就是血管壁

抗脂质沉积能力下降

第一 是血管内皮细胞受损

比较容易导致脂质蛋白

浸入到内膜

比如说高血压和吸烟等

可引起内膜损伤

第二 是动脉壁

对脂质的清除能力下降

而老年人的血管壁

对于脂质的清除能力下降

因此动脉粥样硬化的发生

随着年龄的增长逐年增高

第三 影响因素

高血压 血管痉挛

内皮细胞缺氧损伤

使得内膜损伤

容易脂质沉积到内膜下

吸烟

尼古丁可以损伤血管内膜

引起脂质的沉积

性别

在更年期以前的女性

动脉粥样硬化发病低

而到了更年期以后

和男性发病一致

提示雌激素

对于动脉粥样硬化发生的抵抗

具有保护作用

年龄

老年人血管壁清除脂质的能力

下降

饮食

饮食主要是

作用在脂质代谢这个环节

内分泌也主要作用在脂质代谢

这个环节

遗传

既可以作用在脂质代谢这个环节

也可以作用在

血管清除脂质能力的这方面

但主要

是作用在脂质代谢障碍这个环节

糖尿病也主要影响在

脂质代谢障碍这个环节

Gateway to Medicine: An Introduction to the Field of Medicine课程列表:

CH01 Smog and Lung Diseases

-01-The basic condition of the air

--The basic condition of the air

-02-What is smog and its influence to the body

--What is smog and its influence to the body

-03-The structure and the function of human respiratory system

--The structure and the function of human respiratory system

-04-How the smog cause the human respiratory system disease

--How the smog cause the human respiratory system disease

-05-Asthma

--Asthma

-Exercise 01

-06-COPD

--COPD

-07-Lung cancer Ⅰ

--Lung cancer Ⅰ

-08-Lung cancer Ⅱ

--Lung cancer Ⅱ

-Exercise 02

CH02 Pregnancy and Delivery

-01 Dissection of genital organs

--Dissection of genital organs

-Exercise 01

-02 The formation of embryo and fetal appendage

--The formation of embryo and fetal appendage

-Exercise 02

-03 Characteristic of embryonic and fetal development

--Characteristic of embryonic and fetal development

-04 Maternal changes during pregnancy

--Maternal changes during pregnancy

-05 Four factors that affect childbirth

--Four factors that affect childbirth

-06 Mechanism of labor

--Mechanism of labor

CH03 Children’s nutrition requirement and infant feeding

-01 The energy requirement and the metabolic characteristics of kids

--The energy requirement and the metabolic characteristics of kids

-02 Need of the nutrition and metabolism of kids Ⅰ

--Need of the nutrition and metabolism of kids Ⅰ

-Exercise 01

-03 Need of the nutrition and metabolism of kids Ⅱ

--Need of the nutrition and metabolism of kids Ⅱ

-Exercise 02

-04 Guided feeding of infant Ⅰ

--Guided feeding of infant Ⅰ

-Exercise 03

-05 Guided feeding of infant Ⅱ

--Guided feeding of infant Ⅱ

-06 Guided feeding of infant Ⅲ

--Guided feeding of infant Ⅲ

CH04 Get to know about tumor

-01 Introduction

--Introduction

-02 What is tumor

--What is tumor

-03 The general shape of tumor

--The general shape of tumor

-04 The atypia of the tumor

--The atypia of the tumor

-05 Name and classification of the tumor

--Name and classification of the tumor

-Exercise 01

-06 The growing type of the tumor

--The growing type of the tumor

-07 Spread of tumor

--Spread of tumor

-Exercise 02

-08 The grading and staging of tumors and the effects to the body

--The grading and staging of tumors and the effects to the body

-09 The difference between benign and malignant tumors

--The difference between benign and malignant tumors

-10 The environmental causes of cancer

--The environmental causes of cancer

-11 Heredity and tumor

--Heredity and tumor

CH05 Emergency (Cardiopulmonary resuscitation) and Disaster Medicine

-01 Overview

--Overview

-02 Sudden cardiac arrest

--Sudden cardiac arrest

-Exercise 01

-03 Non-professional life support

--Non-professional life support

-Exercise 02

-04 Professional life support

--Professional life support

-Exercise 03

-05 Adult advanced life support Ⅰ

--Adult advanced life support Ⅰ

-Exercise 04

-06 Adult advanced life support Ⅱ

--Adult advanced life support Ⅱ

-Exercise 05

-07 Electric defibrillation

--Electric defibrillation

CH06 Cardiovascular disease (Atherosclerosis and hypertension)

-01 Introduction

--Introduction

-02 Risk factors and pathogenesis of atherosclerosis

--Risk factors and pathogenesis of atherosclerosis

-03 Pathological changes of atherosclerosis

--Pathological changes of atherosclerosis

-Exercise 01

-04 Atherosclerosis of vital organs

--Atherosclerosis of vital organs

-05 Coronary atherosclerotic heart disease

--Coronary atherosclerotic heart disease

-Tips 03

--Tips 03

-06 Primary hypertension

--Primary hypertension

-Exercise 02

-07 The etiology and pathogenesis of hypertension

--The etiology and pathogenesis of hypertension

-08 The types and pathologic changes of essential hypertension

--The types and pathologic changes of essential hypertension

-Exercise 03

CH07 The war that never ends——Human versus virus

-01 Overview Ⅰ

--Overview Ⅰ

-02 Overview Ⅱ

--Overview Ⅱ

-03 What is virus

--What is virus

-Exercise 01

-04 The structure and functions of influenza viruses

--The structure and functions of influenza viruses

-Exercise 02

-05 Different type of influenza viruses

--Different type of influenza viruses

-Exercise 03

-06 Bird flu

--Bird flu

-Exercise 04

-07 Street virus

--Street virus

-Exercie 05

CH08 The germs that gastric acid can't kill——Helicobacter pylori and Gastric diseases

-01 Introduction

--Introduction

-02 Chronic gastritis caused by helicobacter pylori infection

--Chronic gastritis caused by helicobacter pylori infection

-Exercise 01

-03 Helicobacter pylori causes peptic ulcer

--Helicobacter pylori causes peptic ulcer

-Exercise 02

-04 Pathological changes of peptic ulcer

--Pathological changes of peptic ulcer

-Exercise 03

-05 Gastric cancer

--Gastric cancer

CH09 The movement and injury of human body——The motor function of human body

-01 The evolution of biological motion

--The evolution of biological motion

-02 Biomechanics of human motion

--Biomechanics of human motion

-Exercise 01

-03 The perfect unity of function and structure

--The perfect unity of function and structure

-Exercise 02

-04 A brief history of trauma orthopedic development Ⅰ

--A brief history of trauma orthopedic development Ⅰ

-05 A brief history of trauma orthopedic development Ⅱ

--A brief history of trauma orthopedic development Ⅱ

-Exercise 03

-06 Sprain and fracture of the ankle joint

--Sprain and fracture of the ankle joint

-Exercise 04

-07 Ankle sprain

--Ankle sprain

-Exercise 05

-08 Prevention of ankle sprain

--Prevention of ankle sprain

Final Exam

-Final Exam

Risk factors and pathogenesis of atherosclerosis笔记与讨论

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